Vitamin C Increases Diamine Oxidase
The humble vitamin C increases diamine oxidase making it one of the simplest and cheapest treatments for histamine intolerance.
Here is a quick summary of current research findings:
- Dosage recommendations are between 1 – 3 grams a day, with 2 grams a general recommendation.
- Vitamin C increases diamine oxidase which then metabolises excess histamine.
- Vitamin C does not stop histamine degranulation from mast cells. It does not affect tryptase levels.
- Chewable tablets (absorbed orally) are the most rapidly absorbed (including by the brain) in an emergency.
- Vitamin C can also reduce nausea and sea-sickness.
What does this mean in practice:
- Our body does not manufacture or store vitamin c. This means we need to consume vitamin c daily.
- It is important to commence with a low dosage and build very slowly or you will get diarrhea. Trust me!
- When selecting a supplement it is important to consider a supplement with the minimum number of fillers and additives. I take the Seeking Health Brand of Optimal Liposomal Vitamin C which is one of the few I tolerate.
- If you are particularly sensitive then you may need to start with bolstering your vitamin c through your diet first. It may however be difficult to obtain 2 grams consistently solely through your diet.
- Quercetin is not needed to bolster diamine oxidase.
If you want to start with food, then Vitamin C is found in reasonable quantities, in a broad range of fruit and vegetables. To boost levels further, there are three super-nutrients, which are easy to slip into a smoothie or two:
- Kakadu Plum (Gubinge) – Kakadu plum is a native fruit of Australia. It has the highest concentration of Vitamin C of any food. Just 15g will provide 2g of Vitamin C. I use the Loving Earth Wild Harvested Gubinge.
- Camu Camu – Camu camu is a native fruit of Peru. It has a high concentration of Vitamin C (second only to Kakadu Plum). Just 17g will provide 2g of Vitamin C making it a substitute for Kakadu Plum. It has a consistency and taste similar to Kakadu Plum so I tend to just use one or the other.
- Rosehips – Whilst Rosehips contain less vitamin C (relative to Kakadu plum or Camu Camu) they also contain high levels of anti-oxidants and flavonoids. They are also a relative of the apple making them a perfect marriage.
Whilst these super-nutrients have a slightly bitter taste, I find slipped into a fruit smoothie, I am none the wiser.
So if you want to treat your histamine flares naturally, or are stuck trying to empty your histamine bucket, rather than reaching for an anti-histamine, think about reaching for some vitamin c instead. Its that simple.