Posts Tagged ‘mast cell activation disorder’
The science on how to heal is growing rapidly.
Recently, Dr. Naviaux published a journal article that organizes the current knowledge on how to heal. I consider it a seminal piece of work.
We now know that healing happens on a cellular (not an organ) level.
This is hardly news to those who suffer from mast cell activation. However, the focus of Naviaux’s work is identifying what is blocking the cell.
What if rather than perpetually blocking the mast cell’s response we could remove the blocking factor and restore cellular health?
Naviaux has suggested four distinct stages of healing based on distinct cellular characteristics.
The four stages are the;
- Health cycle,
- Cell danger response 1 (CDR1),
- Cell danger response 2 (CDR 2), and
- Cell danger response 3 (CDR3).
The cell danger response is Naviaux’s term for mast-cell activation.
Importantly, Naviaux has also provisionally organized over 100 conditions, into each of these stages providing a working hypothesis on where targeted solutions can promote healing.
Addressing electro-magnetic fields (EMFs) has had a profound impact on my health and made me rethink the root cause of mast-cell activation.
Simplistically, EMFs are the electrical or magnetic charge that is associated with the use of wi-fi, technology, and electrical current. I’ll explain more as we go.
I have to admit that it took me a long time to really understand that EMFs could be taking its toll on my own health.
I first heard Dr. Dietrich Klinghardt give a lecture on it about two years ago. I heard him give a lecture on it again recently, and finally realized the paramount importance of this topic.
Speaking personally, resistance and denial, were my justification for not moving this issue further up my to-do-list.
Firstly, EMFs are difficult to relate to. How can something you cannot see cause health issues? I think that is what made it easy for me to think that it was not happening to me. But it was.
Secondly, the unknown seemed overwhelming. Having just mold remediated my house, the idea of EMF remediating my house, was overwhelming. But I hired a meter and measured the sources of the EMFs in my house, found out they were really only a few things, and set about resolving them one at a time.
Thirdly, there’s the issue of convenience. I’m all for convenience, but if someone had of told me that if I made a few simple changes (not many – and yes I still have an iPhone) I’d have more energy, a good night sleep, and my brain would feel less ‘wired’, it would have been my first priority.
Fourthly, dopamine addiction is real. The hits of dopamine we get from the endless texts, alerts, posts, and games are addictive. The thing is by putting my iPhone to aeroplane mode, and not hearing the constant alerts, I’m spending more time on the things that make me happy.
Regardless of the importance of this matter to you, I hope to give you a simple overview, so that you can make an informed decision on how you use technology. Simple safety strategies, like putting a seatbelt on when in a moving car, can enable you to use technology safely.
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The realization that Metformin blocks the diamine oxidase enzyme led me to research the medicines that cause histamine intolerance.
Diamine oxidase is the enzyme within the intestine which breaks down biogenic amines (including histamine). When the level of histamine consumption exceeds the capacity of diamine oxidase to break it down histamine intolerance occurs.
By blocking diamine oxidase Metformin can cause histamine intolerance. It did for me.
Let me make it clear from the outset I am not a medical doctor and you should not stop any medicines without talking to your doctor.
All medicines have risks and benefits.
I am providing this information so that you can partner with your doctor about those risks and benefits and make an informed choice. It may be that on balance it may be best to take the medicine and manage the histamine intolerance.
Also, there are many reasons that a medicine might be acting promiscuously.
In this blog post, I am simply addressing one aspect which is medicines that block the diamine oxidase enzyme and those that release histamines.
I have previously written about pharmacogenomics.
And finally, whilst there has been some research into medicines that block the diamine oxidase enzyme or release histamines, this is not a requirement prior to listing medicines with the regulatory authorities.
Simplistically, medicines when listed only are required to demonstrate what problem they solve not necessarily all the unintended problems if any they may create. This means that despite my best efforts this information may be incomplete.
With that said, drug allergies are a common cause of histamine intolerance type symptoms, at least in my client base, and the role that medicine plays in both optimizing health, and causing unwanted side effects is worth considering.
For some time now, I have been studying retroviruses and their link to chronic illnesses, including mast cell activation syndrome and chronic fatigue syndrome.
Retroviruses trigger the cell danger response or mast cell activation.
I started by following the work of Dr. Judy Mikovits whose ground-breaking research, identified that retroviruses were linked to many chronic illnesses.
She outlined her research in the ground-breaking book Plague: One Scientists Intrepid Search for the Truth about Human Retroviruses and Chronic Fatigue Syndrome (ME/CFS), Autism, and Other Diseases.
From there I was mentored by a functional practitioner with access to Dr. Judy Mikovits on her recommended retrovirus protocol. I’ve implemented this protocol with some clients with chronic illnesses with profound results.
More recently, Dr. Klinghardt, who I have trained with has started teaching his approach to retroviruses.
His approach is based on the work of Dr. Mikovits but brings with it extensive clinical experience. Dr. Klinghardt uses a form of applied kinesiology called ART to individualize solutions. I find his methods extremely accurate and am increasingly using it with all my clients.
This work has the capacity to change the way we address chronic illness and specifically mast cell activation, chronic fatigue syndrome, and the cell danger response in general.





