Posts Tagged ‘mast cell stabiliser’

Cell Danger Response

Cell Danger Response : Rethinking Mast Cell Activation

May 1, 2018  |  Blog, Chronic Fatigue, Histamine Intolerance  |  Comments Off on Cell Danger Response : Rethinking Mast Cell Activation

The work of Naviaux on cell danger response has advanced our understanding of chronic illnesses.

I believe his work fundamentally shifts our thinking on the root cause of many diseases including mast cell activation, histamine intolerance, and chronic fatigue syndrome.

So often on this journey to restore our health we are seeking a diagnosis. Many, myself included, get the diagnosis only to find that stops rather than starts the restoration of health.

What we are missing is the middle bit. The bit that sits between wellness and disease. Health is a skill-set, not a diagnosis.

The cell danger response provides an explanation for this middle bit and underlies much of what I have come to believe about optimizing health.  It is the approach I have used to significantly restore my own health.

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CYP450 Inhibitors and Inducers

CYP450 Enzymes: A Complete List of the Most Potent Inhibiting and Inducing Foods and Bioactives

I have been wanting to write this post for some time about CYP450 inhibitors: a complete list of the most potent inhibiting and inducing foods and bio-actives for some time. This information has made one of the biggest difference to my health and wellbeing and continues to do so.

It has become abundantly clear to me that the trigger of my mast cell activation was CYP450 mutations and prescription medication. I am also not alone as around 10% of the population have a similar mutation.

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Vitamin B6 Increases Diamine Oxidase

Why Your Vitamin B6 Level Is Important

Vitamin B6 is a cluster of compounds (not just one)  that is a co-factor in over 100 biochemical reactions in the body which is why your Vitamin B6 level is important.

Here are just a few of the things that studies show that it does for you:

  • Increases diamine oxidase plasma levels.
  • Degrading glutamates and MSG.
  • Metabolises proteins.
  • Reduces oxalate levels
  • Inhibits the degranulation of mast-cells.
  • Moderates cortisol levels.
  • Regulates blood sugar levels and glucose tolerance.
  • Converts ALA to DHA.
  • Acts as a potent anti-oxidant.
  • Synthesises neurotransmitters; serotonin, dopamine, and GABA, and norepinephrine.
  • Relieves PMS, dermatitis, mosquito bites, irritability, depression, and short-term memory issues.

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Histamine in Nervous System

The Therapeutic Use of Probiotics For Histamine Intolerance

December 15, 2014  |  Blog, Histamine Intolerance  |  23 Comments

Recently Chris Kresser did a podcast on histamine intolerance in which he discussed histamine degrading probiotics. I have great respect for Chris whom I have personally consulted on all things histamine. Unfortunately, in my opinion, his information was out of date.

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